INDICATION

Onaxen is indicated for -

- Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy

- Prevention of nausea and vomiting associated with radiotherapy

- Prevention of post operative nausea and vomiting

DOSAGE & ADMINISTRATION

Prevention of chemotherapy induced nausea & vomiting (CINV):

Adult- Oral solution: The recommended adult oral dosage of Onaxen (Ondansetron) is 10 ml thrice daily in highly emetogenic chemotherapy. In case of moderately emetogenic chemotherapy the oral dose is 10 ml of Onaxen (Ondansetron) oral solution given twice daily.

Pediatric patients- Oral solution: For pediatric patients of 4 to 11 years of age, the dosage is 5 ml of Onaxen solution that should be administered 3 times a day for 1 to 2 days after completion of chemotherapy.

Radiotherapy induced nausea and vomiting:

Adult- Oral solution: The recommended oral dosage is 10 ml of Onaxen oral solution 3 times daily.

Post operative nausea & vomiting (PONV):

Adult- Oral solution: The recommended dosage is 20 ml of Onaxen oral solution 1 hour before induction of anesthesia.

Dosage adjustment for patients with impaired hepatic function- Oral soluton: The total daily dose of 10 ml should not be exceeded. 

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