INDICATIONS Adjuvant Colon Cancer: Patients with Dukes C colon cancer Metastatic Colorectal Cancer: First-line as monotherapy when treatment with Fluoropyrimidine therapy alone is preferred ⚫Metastatic Breast Cancer: In combination with Docetaxel after failure of prior anthracycline - containing therapy As monotherapy in patients resistant to both paclitaxel and an anthracycline-containing regimen DOSAGE AND ADMINISTRATION • Take Capecitabine with water within 30 minutes after a meal. • Monotherapy: 1250 mg/m2 twice daily orally for 2 weeks followed by a one week rest period in 3-week cycles. •Adjuvant treatment is recommended for a total of 6 months (8 cycles). In combination with Docetaxel, the recommended dose of Capecitabine is 1250 mg/m2 twice daily for 2 weeks followed by a 7-day rest period, combined with Docetaxel at 75 mg/m2 as a 1-hour IV infusion every 3 weeks. • Capecitabine dosage may need to be individualized to optimize patient management. Reduce the dose of Capecitabine by 25% in patients with moderate renal impairment.
Tyrosine kinase inhibitor
Tyrosine kinase inhibitor
Tyrosine kinase inhibitor
Tyrosine kinase inhibitor
Tyrosine kinase inhibitor
kinase inhibitors
Progestin class
Androgen receptor inhibitors
IDH1 inhibitor
polymerase (PARP) inhibitor